Long‑term complications

Long‑term complications include:1

  • Chronic arterial hypertension
  • Renal impairment
  • Chronic liver damage
  • Hepatocellular carcinoma

Some patients experience chronic neuropathic pain, which may account for an increased risk for depression and suicide.1

Reference:

Anderson KE, Bloomer JR, Bonkovsky HL, et al. Recommendations for the Diagnosis and Treatment of the Acute Porphyrias. Ann Intern Med 2005;142:439‑450.